In my previous experience with Unity, I have had an organized level structure where each level instance was easily separated into a different scene.

For my current project, it would be much more natural to avoid such transitions, and instead disable or remove GameObject instances far from the player's position, and of course loading them in when necessary.

It strikes me that this must be how titles like Gone Home & Firewatch must have been made, and while my game won't be huge in scope, it will be bigger than those ("distance" wise).

Basically, I don't want to get halfway down this road and realize I've made a terrible mistake, so any input is appreciated. Are there disadvantages to using a singular scene in Unity?