Flagship Pioneering

For 25 years, Flagship Pioneering has been turning bold ideas into transformative realities — pushing the boundaries of knowledge to create a better future for people and the planet. The people who drive our ecosystem forward share more than ambition — they share a pioneering mindset. Together, we’re not just advancing science; we’re taking bigger leaps that redefine what’s possible. Read why employees of Alltrna, Tessera Therapeutics, and Valo Health pioneer. #BiggerLeaps #WeAreFlagship

In the latest episode of Harvard Business Review's IdeaCast, Flagship Founder & CEO Noubar Afeyan joins Alison Beard to discuss how innovative organizations are built, the distinction between managing risk and managing uncertainty, and what sets breakthrough science apart from incremental progress. Catch the full episode here: https://lnkd.in/gmPaqRhN

Now recruiting for the AI/ML Track.💡 The Flagship Fellowship AI/ML Track is a unique opportunity to creatively apply cutting-edge computational thinking to our company creation process. We're looking for entrepreneurial computational scientists excited to invent and build world-changing companies in AI, technology, and life-sciences. Learn more and apply here: https://lnkd.in/erQQD5AU

At YourBio, we’re reimagining what the modern blood collection process can and should look like: simpler, easier, and more human. We look forward to continuing this mission with hims & hers. Read more about the agreement announced today, which is subject to customary regulatory approvals and closing conditions: https://lnkd.in/eAA7apMj

Check out the Boston Business Journal this week, featuring our Founder & CEO, Noubar Afeyan, highlighting Flagship’s 25-year journey of pioneering a new model of company creation. Noubar reflects on the mindset behind our approach, the evolution of the biotech industry, and how Flagship is preparing for the next chapter of innovation. Read the full story here: https://lnkd.in/eVZnj5RQ

For Giving Tuesday, we’re proud to highlight the many ways our Flagship colleagues have given back this year, alongside partners like Life Science Cares Boston and One8 Applied Learning Hub. Employees have volunteered at our annual Day of Service, hosted a sock drive at Flagship’s 25th Anniversary event, mentored students in STEM, donated food shelf-stable items this fall, and so much more throughout the year!

The start of Generate’s late-stage clinical trial for its AI-engineered medicine for asthma is yet another powerful example of the transformative impact of generative technologies on biology, producing and accelerating the development of therapies that couldn’t be designed any other way. Recruiting patients from 45 countries, the trial reflects the same global reach and impact of generative AI on drug design.

Tessera’s Gene Writing and delivery technology offers the promise of a one-time, lasting treatment for AATD—addressing the genetic root of a disease for which no such options exist today. This collaboration brings together #FlagshipFounded Tessera’s pioneering science with Regeneron’s industry-leading capabilities in genetics, creating a path toward new possibilities for patients and their families. 

Flagship Pioneering announces Michael Nally, CEO of #FlagshipFounded Generate:Biomedicines and Flagship CEO-Partner, as the recipient of this year’s Bigger Leaps Award.    At Generate, Mike has paired scientific vision with operational discipline, and — just as importantly — has built a culture that turns aspiration into achievement, uniting more than 300 “Generators” around a shared mission to engineer the future of medicine. For more: https://bit.ly/3Ki9qHn