Suppose you have a SQLDataSource that looks like this:
<asp:SqlDataSource ID="sqldsSample" runat="server"
ConnectionString="<%$ ConnectionStrings:myConnectionString %>"
SelectCommand="SELECT [col1], [col2] FROM [tbl] WHERE [col3] = @val) ORDER BY [col1] DESC;">
<SelectParameters>
<asp:Parameter DefaultValue="False" Name="val" Type="Boolean" />
<asp:Parameter DefaultValue="" Name="val2" Type="String" />
</SelectParameters>
</asp:SqlDataSource>
Just assume you have decided you want to declare the 'val2' parameter here and you don't want to bother with adding and/or removing parameters later in the code-behind (say, to change the SelectCommand to do some filtering with some extra criteria).
It will fail without an error - the control will just show up empty.