you can replace your whole loop by this oneliner (is this really a oneliner when using if on a single line?):
if any(calcSth(a,b)>60 for a,b in myList): return True
any will stop testing as soon as a a,b matches the condition.
Also, according to your last edit, if you're planning to return False right after your loop if nothing matches, you can replace the whole routine by:
return any(calcSth(a,b)>60 for a,b in myList)
EDIT: about the performance, I made a quick test, and as predicted, the any construct is roughly 20% faster with the input data I provided (35 items and matching condition in the end, kind of "worst case"). If the matching condition is at the beginning of the list, the difference is very small between both constructions.
return Falseat the end:return any(calcSth(a,b)>60 for a,b in myList)